4BN5
Structure of human SIRT3 in complex with SRT1720 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL | polymer | 281 | 31253.0 | 12 | UniProt (Q9NTG7) Pfam (PF02146) In PDB | HOMO SAPIENS (HUMAN) | HSIRT3, REGULATORY PROTEIN SIR2 HOMOLOG 3, SIR2-LIKE PROTEIN 3 |
| 2 | E, F, G, H, A... | CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 662.5 | 12 | Chemie (CNA) | |||
| 3 | E, F, G, H, A... | N-{2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl}quinoxaline-2-carboxamide | non-polymer | 469.6 | 12 | Chemie (SR7) | |||
| 4 | E, F, G, H, A... | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 5 | C, K, D, L | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 375036.1 | |
| Non-Polymers* | Number of molecules | 40 |
| Total formula weight | 14737.5 | |
| All* | Total formula weight | 389773.7 |
