4BLA

Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory subdomain (crystal form II)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG	polymer	756	84054.7	4	UniProt (P0AEX9) UniProt (Q9UMX1) Pfam (PF01547) Pfam (PF05076) Pfam (PF12470) In PDB	ESCHERICHIA COLI

Sequence modifications

A, B, C, D: 2 - 368 (UniProt: P0AEX9)

PDB	External Database	Details
Met 1	-	expression tag
Thr 3	Ile 28	engineered mutation
Ala 360	Glu 385	engineered mutation
Ala 363	Lys 388	engineered mutation
Ala 364	Asp 389	engineered mutation
Asn 368	Arg 393	engineered mutation
Ala 369	-	linker
Ala 370	-	linker
Ala 371	-	linker
Val 749	-	expression tag
Glu 750	-	expression tag
His 751	-	expression tag
His 752	-	expression tag
His 753	-	expression tag
His 754	-	expression tag
His 755	-	expression tag
His 756	-	expression tag

A, B, C, D: 372 - 618 (UniProt: Q9UMX1)
A, B, C, D: 626 - 748 (UniProt: Q9UMX1)

PDB	External Database	Details
Pro 619	-	linker
Ser 620	-	linker
Arg 621	-	linker
Gly 622	-	linker
Glu 623	-	linker
Asp 624	-	linker
Pro 625	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	336218.9
All*	Total formula weight	336218.9

*Water molecules are not included.