4BL8

Crystal structure of full-length human Suppressor of fused (SUFU)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG	polymer	831	92492.2	2	UniProt (P0AEX9) UniProt (Q9UMX1) Pfam (PF01547) Pfam (PF05076) Pfam (PF12470)	ESCHERICHIA COLI
2	C, D (C, D)	alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose	branched		342.3	2	In PDB BIRD (PRD_900001) GlyTouCan (G07411ON)		alpha-maltose

Sequence modifications

A, B: 2 - 368 (UniProt: P0AEX9)

PDB	External Database	Details
Met 1	-	expression tag
Thr 3	Ile 28	engineered mutation
Ala 360	Glu 385	engineered mutation
Ala 363	Lys 388	engineered mutation
Ala 364	Asp 389	engineered mutation
Asn 368	Arg 393	engineered mutation
Ala 369	-	linker
Ala 370	-	linker
Ala 371	-	linker
Val 824	-	expression tag
Glu 825	-	expression tag
His 826	-	expression tag
His 827	-	expression tag
His 828	-	expression tag
His 829	-	expression tag
His 830	-	expression tag
His 831	-	expression tag

A, B: 372 - 823 (UniProt: Q9UMX1)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	184984.3
Branched	Number of molecules	2
	Total formula weight	684.6
All*	Total formula weight	185668.9

*Water molecules are not included.