4BL8

Crystal structure of full-length human Suppressor of fused (SUFU)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0003714	molecular_function	transcription corepressor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005929	cellular_component	cilium
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006974	biological_process	DNA damage response
A	0007165	biological_process	signal transduction
A	0007286	biological_process	spermatid development
A	0008013	molecular_function	beta-catenin binding
A	0008643	biological_process	carbohydrate transport
A	0015144	molecular_function	carbohydrate transmembrane transporter activity
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0019901	molecular_function	protein kinase binding
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0034219	biological_process	carbohydrate transmembrane transport
A	0034289	biological_process	detection of maltose stimulus
A	0042308	biological_process	negative regulation of protein import into nucleus
A	0042597	cellular_component	periplasmic space
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0045668	biological_process	negative regulation of osteoblast differentiation
A	0045879	biological_process	negative regulation of smoothened signaling pathway
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0060326	biological_process	cell chemotaxis
A	0097542	cellular_component	ciliary tip
A	0097546	cellular_component	ciliary base
A	0140311	molecular_function	protein sequestering activity
A	1901982	molecular_function	maltose binding
A	2001040	biological_process	positive regulation of cellular response to drug
B	0000122	biological_process	negative regulation of transcription by RNA polymerase II
B	0003714	molecular_function	transcription corepressor activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005929	cellular_component	cilium
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006974	biological_process	DNA damage response
B	0007165	biological_process	signal transduction
B	0007286	biological_process	spermatid development
B	0008013	molecular_function	beta-catenin binding
B	0008643	biological_process	carbohydrate transport
B	0015144	molecular_function	carbohydrate transmembrane transporter activity
B	0015768	biological_process	maltose transport
B	0016020	cellular_component	membrane
B	0019901	molecular_function	protein kinase binding
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0034219	biological_process	carbohydrate transmembrane transport
B	0034289	biological_process	detection of maltose stimulus
B	0042308	biological_process	negative regulation of protein import into nucleus
B	0042597	cellular_component	periplasmic space
B	0042956	biological_process	maltodextrin transmembrane transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0045668	biological_process	negative regulation of osteoblast differentiation
B	0045879	biological_process	negative regulation of smoothened signaling pathway
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0055085	biological_process	transmembrane transport
B	0060326	biological_process	cell chemotaxis
B	0097542	cellular_component	ciliary tip
B	0097546	cellular_component	ciliary base
B	0140311	molecular_function	protein sequestering activity
B	1901982	molecular_function	maltose binding
B	2001040	biological_process	positive regulation of cellular response to drug

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO108-ASN125

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"27234298","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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