4BK5

crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 (amine-methylated sample)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	EPHRIN TYPE-A RECEPTOR 4	polymer	568	62649.3	1	UniProt (P54764) Pfam (PF01404) Pfam (PF07699) Pfam (PF00041) In PDB	HOMO SAPIENS (HUMAN)	EPH-LIKE KINASE 8, EK8, HEK8, TYROSINE-PROTEIN KINASE TYRO1, TYROSINE-PROTEIN KINASE RECEPTOR SEK
2	C	EPHRIN-A5	polymer	180	20689.6	1	UniProt (P52803) Pfam (PF00812) In PDB	HOMO SAPIENS (HUMAN)	AL-1, EPH-RELATED RECEPTOR TYROSINE KINASE LIGAND 7, LERK-7

Sequence modifications

A: 20 - 547 (UniProt: P54764)

PDB	External Database	Details
Met -11	-	expression tag
Gly -10	-	expression tag
Ile -9	-	expression tag
Leu -8	-	expression tag
Pro -7	-	expression tag
Ser -6	-	expression tag
Pro -5	-	expression tag
Gly -4	-	expression tag
Met -3	-	expression tag
Pro -2	-	expression tag
Ala -1	-	expression tag
Leu 0	-	expression tag
Leu 1	-	expression tag
Ser 2	-	expression tag
Leu 3	-	expression tag
Val 4	-	expression tag
Ser 5	-	expression tag
Leu 6	-	expression tag
Leu 7	-	expression tag
Ser 8	-	expression tag
Val 9	-	expression tag
Leu 10	-	expression tag
Leu 11	-	expression tag
Met 12	-	expression tag
Gly 13	-	expression tag
Cys 14	-	expression tag
Val 15	-	expression tag
Ala 16	-	expression tag
Glu 17	-	expression tag
Thr 18	-	expression tag
Gly 19	-	expression tag
Gly 548	-	expression tag
Thr 549	-	expression tag
Lys 550	-	expression tag
His 551	-	expression tag
His 552	-	expression tag
His 553	-	expression tag
His 554	-	expression tag
His 555	-	expression tag
His 556	-	expression tag

C: 31 - 171 (UniProt: P52803)

PDB	External Database	Details
Met 0	-	expression tag
Gly 1	-	expression tag
Ile 2	-	expression tag
Leu 3	-	expression tag
Pro 4	-	expression tag
Ser 5	-	expression tag
Pro 6	-	expression tag
Gly 7	-	expression tag
Met 8	-	expression tag
Pro 9	-	expression tag
Ala 10	-	expression tag
Leu 11	-	expression tag
Leu 12	-	expression tag
Ser 13	-	expression tag
Leu 14	-	expression tag
Val 15	-	expression tag
Ser 16	-	expression tag
Leu 17	-	expression tag
Leu 18	-	expression tag
Ser 19	-	expression tag
Val 20	-	expression tag
Leu 21	-	expression tag
Leu 22	-	expression tag
Met 23	-	expression tag
Gly 24	-	expression tag
Cys 25	-	expression tag
Val 26	-	expression tag
Ala 27	-	expression tag
Glu 28	-	expression tag
Thr 29	-	expression tag
Gly 30	-	expression tag
Gly 172	-	expression tag
Thr 173	-	expression tag
Lys 174	-	expression tag
His 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag
His 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83338.9
All*	Total formula weight	83338.9

*Water molecules are not included.