4BJU
Genetic and structural validation of Aspergillus fumigatus N- acetylphosphoglucosamine mutase as an antifungal target
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | N-ACETYLGLUCOSAMINE-PHOSPHATE MUTASE | polymer | 549 | 60008.9 | 2 | UniProt (B0XPI4) Pfam (PF02878) Pfam (PF21405) Pfam (PF21404) Pfam (PF00408) | ASPERGILLUS FUMIGATUS | N-ACETYLPHOSPHOGLUCOSAMINE MUTASE |
| 2 | C, D (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 549 (UniProt: B0XPI4)
| PDB | External Database | Details |
|---|---|---|
| - | Val 85 | deletion |
| - | Ser 86 | deletion |
| - | Ser 87 | deletion |
| - | Tyr 88 | deletion |
| - | Gly 89 | deletion |
| - | Thr 90 | deletion |
| - | Phe 91 | deletion |
| - | Asp 92 | deletion |
| - | Gly 93 | deletion |
| - | Gly 94 | deletion |
| - | Met 95 | deletion |
| - | Lys 96 | deletion |
| - | Gly 97 | deletion |
| - | Glu 98 | deletion |
| - | Phe 99 | deletion |
| - | Ala 100 | deletion |
| - | Asp 101 | deletion |
| Leu 291 | Val 308 | conflict |
| Glu 467 | Asp 484 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120017.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 48.6 | |
| All* | Total formula weight | 120066.5 |
