4BJU

Genetic and structural validation of Aspergillus fumigatus N- acetylphosphoglucosamine mutase as an antifungal target

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004610	molecular_function	phosphoacetylglucosamine mutase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0006048	biological_process	UDP-N-acetylglucosamine biosynthetic process
A	0016853	molecular_function	isomerase activity
A	0016868	molecular_function	intramolecular phosphotransferase activity
A	0046349	biological_process	amino sugar biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0071555	biological_process	cell wall organization
B	0000287	molecular_function	magnesium ion binding
B	0004610	molecular_function	phosphoacetylglucosamine mutase activity
B	0005975	biological_process	carbohydrate metabolic process
B	0006048	biological_process	UDP-N-acetylglucosamine biosynthetic process
B	0016853	molecular_function	isomerase activity
B	0016868	molecular_function	intramolecular phosphotransferase activity
B	0046349	biological_process	amino sugar biosynthetic process
B	0046872	molecular_function	metal ion binding
B	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 998

Chain	Residue
A	SEP69
A	ASP284
A	ASP286
A	ASP288

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 998

Chain	Residue
B	SEP69
B	ASP284
B	ASP286
B	ASP288

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Functional Information from PROSITE/UniProt

site_id	PS00710
Number of Residues	10
Details	PGM_PMM Phosphoglucomutase and phosphomannomutase phosphoserine signature. GVmVTASHNP

Chain	Residue	Details
A	GLY63-PRO72

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