4BJ3

Integrin alpha2 I domain E318W-collagen complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	INTEGRIN ALPHA-2	polymer	225	25137.4	2	UniProt (P17301) Pfam (PF00092)	HOMO SAPIENS (HUMAN)	CD49 ANTIGEN-LIKE FAMILY MEMBER B, COLLAGEN RECEPTOR, PLATELET MEMBRANE GLYCOPROTEIN IA, GPIA, VLA-2 SUBUNIT ALPHA, CD49B
2	C, D, E (C, D, E)	GFOGER PEPTIDE	polymer	21	2015.1	3	Pfam (PF01391) UniProt (by SIFTS) (Q96A83)	HOMO SAPIENS
3	F, I (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	G (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5	H (A)	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	1	Chemie (BTB)

Sequence modifications

A, B: 142 - 339 (UniProt: P17301)

PDB	External Database	Details
Met 121	-	expression tag
Asn 122	-	expression tag
His 123	-	expression tag
His 124	-	expression tag
His 125	-	expression tag
His 126	-	expression tag
His 127	-	expression tag
His 128	-	expression tag
His 129	-	expression tag
His 130	-	expression tag
His 131	-	expression tag
His 132	-	expression tag
Thr 133	-	expression tag
Ser 134	-	expression tag
Leu 135	-	expression tag
Tyr 136	-	expression tag
Lys 137	-	expression tag
Lys 138	-	expression tag
Ala 139	-	expression tag
Gly 140	-	expression tag
Phe 141	-	expression tag
Glu 340	-	expression tag
Phe 341	-	expression tag
Ile 342	-	expression tag
Val 343	-	expression tag
Thr 344	-	expression tag
Asp 345	-	expression tag
Trp 318	Glu 347	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	56320.2
Non-Polymers*	Number of molecules	4
	Total formula weight	293.3
All*	Total formula weight	56613.5

*Water molecules are not included.