4BDR

Crystal structure of the GluK2 R775A LBD dimer in complex with kainate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2	polymer	261	29539.8	2	UniProt (P42260) Pfam (PF10613) Pfam (PF00060)	RATTUS NORVEGICUS (NORWAY RAT)	GLUTAMATE RECEPTOR 6, GLUR-6, GLUR6
2	C, F (A, B)	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE	non-polymer		213.2	2	Chemie (KAI)
3	D (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	E, G (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5	H, I (A, B)	water	water		18.0	489	Chemie (HOH)

Sequence modifications

A, B: 429 - 544 (UniProt: P42260)

PDB	External Database	Details
Gly 428	-	expression tag
Pro 807	-	expression tag
Arg 808	-	expression tag

A, B: 667 - 806 (UniProt: P42260)

PDB	External Database	Details
Gly 555	-	linker
Thr 566	-	linker
Ala 775	Arg 775	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59079.7
Non-Polymers*	Number of molecules	5
	Total formula weight	507.9
All*	Total formula weight	59587.6

*Water molecules are not included.