4BDQ

Crystal structure of the GluK2 R775A LBD dimer in complex with glutamate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2	polymer	261	29539.8	2	UniProt (P42260) Pfam (PF10613) Pfam (PF00060)	RATTUS NORVEGICUS (NORWAY RAT)	GLUTAMATE RECEPTOR 6, GLUR-6, GLUR6
2	C, E (A, B)	GLUTAMIC ACID	non-polymer		147.1	2	Chemie (GLU)
3	D, F (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4	G, H (A, B)	water	water		18.0	461	Chemie (HOH)

Sequence modifications

A, B: 429 - 544 (UniProt: P42260)

PDB	External Database	Details
Gly 428	-	expression tag
Pro 807	-	expression tag
Arg 808	-	expression tag

A, B: 667 - 806 (UniProt: P42260)

PDB	External Database	Details
Gly 555	-	linker
Thr 566	-	linker
Ala 775	Arg 775	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59079.7
Non-Polymers*	Number of molecules	4
	Total formula weight	340.2
All*	Total formula weight	59419.9

*Water molecules are not included.