4BDO
Crystal structure of the GluK2 K531A-T779G LBD dimer in complex with kainate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2 | polymer | 261 | 29523.8 | 4 | UniProt (P42260) Pfam (PF10613) Pfam (PF00060) | RATTUS NORVEGICUS (NORWAY RAT) | GLUTAMATE RECEPTOR 6, GLUR-6, GLUR6 |
| 2 | E, G, I, K (A, B, C, D) | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE | non-polymer | 213.2 | 4 | Chemie (KAI) PubChem (3816) PubChem (10255) PubChem (73345) PubChem (23616889) PubChem (45039619) PubChem (3083828) PubChem (5317452) PubChem (5318769) PubChem (6453379) PubChem (6604705) PubChem (10036135) PubChem (11095940) PubChem (6603893) PubChem (101994997) PubChem (135037246) | |||
| 3 | F, H, J, M (A, B, C, D) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) PubChem (923) | |||
| 4 | L (D) | GLUTAMIC ACID | non-polymer | 147.1 | 1 | Chemie (GLU) PubChem (611) PubChem (23327) PubChem (33032) | |||
| 5 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 429 - 544 (UniProt: P42260)
A, B, C, D: 667 - 806 (UniProt: P42260)
| PDB | External Database | Details |
|---|---|---|
| Gly 428 | - | expression tag |
| Ala 531 | Lys 531 | engineered mutation |
| Pro 807 | - | expression tag |
| Arg 808 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 555 | - | linker |
| Thr 566 | - | linker |
| Gly 779 | Thr 779 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 118095.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1092.0 | |
| All* | Total formula weight | 119187.2 |
