4BDN

Crystal structure of the GluK2 K531A-T779G LBD dimer in complex with glutamate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2	polymer	261	29523.8	4	UniProt (P42260) Pfam (PF10613) Pfam (PF00060)	RATTUS NORVEGICUS (NORWAY RAT)	GLUTAMATE RECEPTOR 6, GLUR-6, GLUR6
2	E, G, I, K (A, B, C, D)	GLUTAMIC ACID	non-polymer		147.1	4	Chemie (GLU)
3	F, H, J, L (A, B, C, D)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
4	M, N, O, P (A, B, C, D)	water	water		18.0	337	Chemie (HOH)

Sequence modifications

A, B, C, D: 429 - 544 (UniProt: P42260)

PDB	External Database	Details
Gly 428	-	expression tag
Ala 531	Lys 531	engineered mutation
Pro 807	-	expression tag
Arg 808	-	expression tag

A, B, C, D: 667 - 806 (UniProt: P42260)

PDB	External Database	Details
Gly 555	-	linker
Thr 566	-	linker
Gly 779	Thr 779	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	118095.1
Non-Polymers*	Number of molecules	8
	Total formula weight	680.5
All*	Total formula weight	118775.6

*Water molecules are not included.