4B9N
Structure of the high fidelity DNA polymerase I correctly bypassing the oxidative formamidopyrimidine-dA DNA lesion.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA POLYMERASE | polymer | 619 | 70446.6 | 1 | UniProt (E1C9K5) Pfam (PF22619) Pfam (PF00476) | GEOBACILLUS STEAROTHERMOPHILUS | |
| 2 | B (B) | 5'-D(*GP*CP*CP*TP*GP*AP*CP*TP*CP*TP*TP*TP*TP)-3' | polymer | 13 | 3908.5 | 1 | GEOBACILLUS STEAROTHERMOPHILUS | ||
| 3 | C (C) | 5'-D(*CP*AP*AP*(FAX)*AP*GP*AP*GP*TP*CP*AP*GP*GP*CP*TP)-3' | polymer | 15 | 4643.1 | 1 | GEOBACILLUS STEAROTHERMOPHILUS | ||
| 4 | D (D) | beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900003) | sucrose | ||
| 5 | E, F, G, H, I (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 6 | J (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | K, L, M (A, B, C) | water | water | 18.0 | 241 | Chemie (HOH) |
Sequence modifications
A: 297 - 876 (UniProt: E1C9K5)
| PDB | External Database | Details |
|---|---|---|
| Met 258 | - | expression tag |
| Ala 259 | - | expression tag |
| Ser 260 | - | expression tag |
| Trp 261 | - | expression tag |
| Ser 262 | - | expression tag |
| His 263 | - | expression tag |
| Pro 264 | - | expression tag |
| Gln 265 | - | expression tag |
| Phe 266 | - | expression tag |
| Glu 267 | - | expression tag |
| Lys 268 | - | expression tag |
| Gly 269 | - | expression tag |
| Ala 270 | - | expression tag |
| Ser 271 | - | expression tag |
| Thr 272 | - | expression tag |
| Ser 273 | - | expression tag |
| Leu 274 | - | expression tag |
| Tyr 275 | - | expression tag |
| Lys 276 | - | expression tag |
| Lys 277 | - | expression tag |
| Ala 278 | - | expression tag |
| Gly 279 | - | expression tag |
| Ser 280 | - | expression tag |
| Ala 281 | - | expression tag |
| Ala 282 | - | expression tag |
| Ala 283 | - | expression tag |
| Val 284 | - | expression tag |
| Leu 285 | - | expression tag |
| Glu 286 | - | expression tag |
| Glu 287 | - | expression tag |
| Asn 288 | - | expression tag |
| Leu 289 | - | expression tag |
| Tyr 290 | - | expression tag |
| Phe 291 | - | expression tag |
| Gln 292 | - | expression tag |
| Gly 293 | - | expression tag |
| Ser 294 | - | expression tag |
| Phe 295 | - | expression tag |
| Thr 296 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 78998.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 504.6 | |
| All* | Total formula weight | 79845.1 |
