4B8Z
Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, rhombohedral crystal form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | GDP-L-FUCOSE SYNTHASE | polymer | 320 | 36001.6 | 4 | UniProt (Q13630) Pfam (PF01370) | HOMO SAPIENS (HUMAN) | GDP-4-KETO-6-DEOXY-D-MANNOSE-3,5-EPIMERASE-4-REDUCTASE, PROTEIN FX, RED CELL NADP(H)-BINDING PROTEIN, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 4E MEMBER 1 |
| 2 | E, G, I, K (A, B, C, D) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
| 3 | F, H, J, L (A, B, C, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 4 | Chemie (GDP) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 8 - 320 (UniProt: Q13630)
| PDB | External Database | Details |
|---|---|---|
| Glu -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Ser -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 144006.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 4746.4 | |
| All* | Total formula weight | 148752.8 |
