4B8W
Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, tetragonal crystal form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GDP-L-FUCOSE SYNTHASE | polymer | 319 | 35872.5 | 2 | UniProt (Q13630) Pfam (PF01370) | HOMO SAPIENS (HUMAN) | GDP-4-KETO-6-DEOXY-D-MANNOSE-3\,5-EPIMERASE- 4-REDUCTASE, PROTEIN FX, RED CELL NADP(H)-BINDING PROTEIN, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 4E MEMBER 1 |
| 2 | C, E (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | D, F (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A, B: -1 - 320 (UniProt: Q13630)
| PDB | External Database | Details |
|---|---|---|
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71745.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2373.2 | |
| All* | Total formula weight | 74118.2 |
