4B86

Crystal structure of the MSL1-MSL2 complex (3.5A)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, E, F, I...	MALE-SPECIFIC LETHAL 1 HOMOLOG	polymer	59	6733.7	6	UniProt (Q68DK7) Pfam (PF16801) In PDB	HOMO SAPIENS (HUMAN)	MSL1, MSL-1, MALE-SPECIFIC LETHAL 1-LIKE 1, MSL1-LIKE 1, MALE-SPECIFIC LETHAL-1 HOMOLOG 1
2	C, D, G, H, K...	MALE-SPECIFIC LETHAL 2 HOMOLOG	polymer	116	13259.5	6	UniProt (Q9HCI7) Pfam (PF16685) In PDB	HOMO SAPIENS (HUMAN)	MSL2, MSL-2, MALE-SPECIFIC LETHAL 2-LIKE 1, MSL2-LIKE 1, MALE-SPECIFIC LETHAL-2 HOMOLOG 1, RING FINGER PROTEIN 184
3	C, D, G, H, K...	ZINC ION	non-polymer		65.4	12	Chemie (ZN)

Sequence modifications

A, B, E, F, I, J: 212 - 267 (UniProt: Q68DK7)

PDB	External Database	Details
Gly 209	-	expression tag
Ala 210	-	expression tag
Met 211	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	119959.2
Non-Polymers*	Number of molecules	12
	Total formula weight	784.9
All*	Total formula weight	120744.1

*Water molecules are not included.