4B7P
Structure of HSP90 with NMS-E973 inhibitor bound
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HEAT SHOCK PROTEIN HSP 90-ALPHA | polymer | 230 | 25810.9 | 1 | UniProt (P07900) Pfam (PF13589) In PDB | HOMO SAPIENS (HUMAN) | HEAT SHOCK 86 KDA, HSP 86, HSP86, RENAL CARCINOMA ANTIGEN NY-REN-38 |
2 | A | 5-[2,4-dihydroxy-6-(4-nitrophenoxy)phenyl]-N-(1-methylpiperidin-4-yl)-1,2-oxazole-3-carboxamide | non-polymer | 454.4 | 1 | Chemie (9UN) | |||
3 | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A: 9 - 236 (UniProt: P07900)
PDB | External Database | Details |
---|---|---|
Gly 7 | - | expression tag |
Pro 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 25810.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 454.4 | |
All* | Total formula weight | 26265.4 |