4B7I
Crystal Structure of Human IgG Fc Bearing Hybrid-type Glycans
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | IG GAMMA-1 CHAIN C REGION | polymer | 218 | 24818.0 | 2 | UniProt (P01857) Pfam (PF07654) | HOMO SAPIENS (HUMAN) | IGG1 FC |
| 2 | C (C) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1381.2 | 1 | In PDB GlyTouCan (G99858XP) | |||
| 3 | D (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A, B: 237 - 446 (UniProt: P01857)
| PDB | External Database | Details |
|---|---|---|
| Thr 447 | - | expression tag |
| Lys 448 | - | expression tag |
| His 449 | - | expression tag |
| His 450 | - | expression tag |
| His 451 | - | expression tag |
| His 452 | - | expression tag |
| His 453 | - | expression tag |
| His 454 | - | expression tag |
| Ala 393 | Thr 276 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49636.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1381.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 51052.7 |
