4B5P

Crystal structure of human alpha tubulin acetyltransferase catalytic domain Q58A variant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	ALPHA-TUBULIN N-ACETYLTRANSFERASE	polymer	200	22785.1	1	UniProt (Q5SQI0) Pfam (PF05301)	HOMO SAPIENS (HUMAN)	ALPHA-TUBULIN ACETYLTRANSFERASE, ALPHA-TAT, TAT, ACETYLTRANSFERASE MEC-17 HOMOLOG
2	B (B)	ALPHA-TUBULIN N-ACETYLTRANSFERASE	polymer	200	22799.1	1	UniProt (Q5SQI0) Pfam (PF05301)	HOMO SAPIENS (HUMAN)	ALPHA-TUBULIN ACETYLTRANSFERASE, ALPHA-TAT, TAT, ACETYLTRANSFERASE MEC-17 HOMOLOG
3	C, E (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4	D, F (A, B)	ACETYL COENZYME *A	non-polymer		809.6	2	Chemie (ACO)
5	G, H (A, B)	water	water		18.0	350	Chemie (HOH)

Sequence modifications

A: 1 - 196 (UniProt: Q5SQI0)

PDB	External Database	Details
Gly -3	-	expression tag
Ala -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag
Ala 58	Gln 58	engineered mutation

B: 1 - 196 (UniProt: Q5SQI0)

PDB	External Database	Details
Gly -3	-	expression tag
Ala -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag
Ala 58	Gln 58	engineered mutation
Ala 91	Gly 91	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45584.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1665.1
All*	Total formula weight	47249.4

*Water molecules are not included.