4B1G
Structure of unliganded human PARG catalytic domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | POLY(ADP-RIBOSE) GLYCOHYDROLASE | polymer | 531 | 61460.1 | 1 | UniProt (Q86W56) Pfam (PF20811) Pfam (PF05028) | HOMO SAPIENS (HUMAN) | |
| 2 | B (A) | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL | non-polymer | 154.3 | 1 | Chemie (DTV) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence modifications
A: 448 - 976 (UniProt: Q86W56)
| PDB | External Database | Details |
|---|---|---|
| Gly 446 | - | expression tag |
| Ser 447 | - | expression tag |
| Ala 616 | Lys 616 | engineered mutation |
| Ala 617 | Gln 617 | engineered mutation |
| Ala 618 | Lys 618 | engineered mutation |
| Ala 688 | Glu 688 | engineered mutation |
| Ala 689 | Lys 689 | engineered mutation |
| Ala 690 | Lys 690 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 61460.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 250.3 | |
| All* | Total formula weight | 61710.4 |
