4AZD

T57V mutant of aspartate decarboxylase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ASPARTATE 1-DECARBOXYLASE	polymer	143	15777.9	2	UniProt (P0A790) Pfam (PF02261)	ESCHERICHIA COLI	L-ASPARTATE-ALPHA-DECARBOXYLASE, ASPARTATE ALPHA-DECARBOXYLASE, ASPARTATE 1-DECARBOXYLASE BETA CHAIN, ASPARTATE 1-DECARBOXYLASE ALPHA CHAIN
2	C, D, E, F (A, B)	MALONATE ION	non-polymer		102.0	4	Chemie (MLI)
3	G, H (A, B)	water	water		18.0	138	Chemie (HOH)

Sequence modifications

A, B: 1 - 126 (UniProt: P0A790)

PDB	External Database	Details
Met -16	-	expression tag
Arg -15	-	expression tag
Gly -14	-	expression tag
Ser -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Val 57	Thr 57	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31555.9
Non-Polymers*	Number of molecules	4
	Total formula weight	408.2
All*	Total formula weight	31964.0

*Water molecules are not included.