Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004068 | molecular_function | aspartate 1-decarboxylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006523 | biological_process | alanine biosynthetic process |
| A | 0015940 | biological_process | pantothenate biosynthetic process |
| A | 0016540 | biological_process | protein autoprocessing |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0004068 | molecular_function | aspartate 1-decarboxylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006523 | biological_process | alanine biosynthetic process |
| B | 0015940 | biological_process | pantothenate biosynthetic process |
| B | 0016540 | biological_process | protein autoprocessing |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MLI B 1118 |
| Chain | Residue |
| A | LYS9 |
| B | ALA74 |
| B | ALA75 |
| B | HOH2014 |
| A | HIS11 |
| A | TRP47 |
| A | ARG54 |
| A | ILE86 |
| B | VAL57 |
| B | TYR58 |
| B | ASN72 |
| B | GLY73 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MLI A 1118 |
| Chain | Residue |
| A | VAL57 |
| A | TYR58 |
| A | ASN72 |
| A | GLY73 |
| A | ALA74 |
| A | ALA75 |
| A | HOH2027 |
| B | LYS9 |
| B | HIS11 |
| B | TRP47 |
| B | ARG54 |
| B | ILE86 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MLI A 1119 |
| Chain | Residue |
| A | ARG12 |
| A | VAL49 |
| A | THR50 |
| A | ILE84 |
| A | HOH2039 |
| B | HIS21 |
| B | ARG102 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MLI A 1120 |
| Chain | Residue |
| A | SER25 |
| A | ASN41 |
| A | TYR58 |
| A | ILE60 |
| A | HOH2026 |
| B | PRO103 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Schiff-base intermediate with substrate; via pyruvic acid","evidences":[{"source":"PubMed","id":"9546220","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Pyruvic acid (Ser)","evidences":[{"source":"PubMed","id":"9546220","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 409 |
| Chain | Residue | Details |
| A | LYS9 | electrostatic stabiliser |
| A | SER25 | covalently attached, electrofuge, electrophile |
| A | TYR58 | activator, increase nucleophilicity, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 3 |
| Details | M-CSA 409 |
| Chain | Residue | Details |
| B | LYS9 | electrostatic stabiliser |
| B | SER25 | covalently attached, electrofuge, electrophile |
| B | TYR58 | activator, increase nucleophilicity, proton acceptor, proton donor |
