4AZC
Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | BETA-N-ACETYLHEXOSAMINIDASE | polymer | 442 | 49649.8 | 1 | UniProt (P49610) Pfam (PF00728) In PDB | STREPTOCOCCUS PNEUMONIAE | GLYCOSIDE HYDROLASE 20 |
2 | B, C, D | BETA-N-ACETYLHEXOSAMINIDASE | polymer | 442 | 49633.7 | 3 | UniProt (P49610) Pfam (PF00728) In PDB | STREPTOCOCCUS PNEUMONIAE | GLYCOSIDE HYDROLASE 20 |
3 | A, B, C, D | (2S,3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-2,3a,5,6,7,7a-hexahydro-1H-pyrano[3,2-d][1,3]thiazole-6,7-diol | non-polymer | 221.3 | 4 | Chemie (NGW) | |||
4 | A, B, C | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
5 | A, C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
6 | water | water | 18.0 | 2051 | Chemie (HOH) |
Sequence modifications
A: 627 - 1064 (UniProt: P49610)
B, C, D: 627 - 1064 (UniProt: P49610)
PDB | External Database | Details |
---|---|---|
Gly 623 | - | expression tag |
Ser 624 | - | expression tag |
His 625 | - | expression tag |
Met 626 | - | expression tag |
Lys 1041 | Leu 1041 | conflict |
PDB | External Database | Details |
---|---|---|
Gly 623 | - | expression tag |
Ser 624 | - | expression tag |
His 625 | - | expression tag |
Met 626 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 198551.0 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 1327.8 | |
All* | Total formula weight | 199878.8 |