4AYC

RNF8 RING domain structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	E3 UBIQUITIN-PROTEIN LIGASE RNF8	polymer	138	16353.1	1	UniProt (O76064) Pfam (PF13920) In PDB	HOMO SAPIENS (HUMAN)	RING FINGER PROTEIN 8
2	B	E3 UBIQUITIN-PROTEIN LIGASE RNF8	polymer	138	16369.1	1	UniProt (O76064) Pfam (PF13920) In PDB	HOMO SAPIENS (HUMAN)	RING FINGER PROTEIN 8
3	A	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	A	N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE	non-polymer		862.1	1	Chemie (CPQ)
5	A, B	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
6	B	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
7	B	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
8		water	water		18.0	58	Chemie (HOH)

Sequence modifications

A: 351 - 485 (UniProt: O76064)

PDB	External Database	Details
Leu 348	-	expression tag
Gly 349	-	expression tag
Ser 350	-	expression tag

B: 351 - 485 (UniProt: O76064)

PDB	External Database	Details
Leu 348	-	expression tag
Gly 349	-	expression tag
Ser 350	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	32722.2
Non-Polymers*	Number of molecules	10
	Total formula weight	1539.4
All*	Total formula weight	34261.6

*Water molecules are not included.