4AYC

RNF8 RING domain structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	E3 UBIQUITIN-PROTEIN LIGASE RNF8	polymer	138	16353.1	1	UniProt (O76064) Pfam (PF13920)	HOMO SAPIENS (HUMAN)	RING FINGER PROTEIN 8
2	B (B)	E3 UBIQUITIN-PROTEIN LIGASE RNF8	polymer	138	16369.1	1	UniProt (O76064) Pfam (PF13920)	HOMO SAPIENS (HUMAN)	RING FINGER PROTEIN 8
3	C, D, E (A)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	F (A)	N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE	non-polymer		862.1	1	Chemie (CPQ) PubChem (16402218) PubChem (44658112) PubChem (45933557) PubChem (46936249) PubChem (71299811) PubChem (3609263) PubChem (446320) PubChem (75361254) PubChem (90277687) PubChem (102565423) PubChem (124867695) PubChem (124905380) PubChem (124905378) PubChem (124919192) PubChem (124933353) PubChem (124933355) PubChem (125027417) PubChem (129891641) PubChem (132470929) PubChem (122130317) PubChem (135639079) PubChem (139981181) PubChem (124837856) PubChem (124905379) PubChem (124905381) PubChem (124919193) PubChem (124919194) PubChem (124919195) PubChem (124933354) PubChem (124933356) PubChem (171036883)
5	G, H, I, J (A, B)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
6	K (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL) PubChem (753)
7	L (B)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL) PubChem (312)
8	M, N (A, B)	water	water		18.0	58	Chemie (HOH)

Sequence modifications

A: 351 - 485 (UniProt: O76064)

PDB	External Database	Details
Leu 348	-	expression tag
Gly 349	-	expression tag
Ser 350	-	expression tag

B: 351 - 485 (UniProt: O76064)

PDB	External Database	Details
Leu 348	-	expression tag
Gly 349	-	expression tag
Ser 350	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	32722.2
Non-Polymers*	Number of molecules	10
	Total formula weight	1539.4
All*	Total formula weight	34261.6

*Water molecules are not included.