4AY9
Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, D, G) | GLYCOPROTEIN HORMONES, ALPHA POLYPEPTIDE | polymer | 92 | 10183.8 | 3 | UniProt (Q96QJ4) Pfam (PF00236) UniProt (by SIFTS) (P01215) | HOMO SAPIENS (HUMAN) | |
| 2 | B, D, F (B, E, H) | FOLLITROPIN SUBUNIT BETA | polymer | 111 | 12500.2 | 3 | UniProt (P01225) Pfam (PF00007) | HOMO SAPIENS (HUMAN) | FOLLICLE-STIMULATING HORMONE BETA SUBUNIT, FSH-B, FSH-BETA, FOLLITROPIN BETA CHAIN |
| 3 | G, H, I (X, Y, Z) | FOLLICLE-STIMULATING HORMONE RECEPTOR | polymer | 350 | 40065.4 | 3 | UniProt (P23945) Pfam (PF01462) Pfam (PF13306) Pfam (PF12369) | HOMO SAPIENS (HUMAN) | FSH-R, FOLLITROPIN RECEPTOR |
| 4 | J, K, L, M, N... (A, B, D, E, G...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) | |||
| 5 | AA, BA, CA, DA, EA... (D, E, G, H, X...) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
X, Y, Z: 17 - 366 (UniProt: P23945)
| PDB | External Database | Details |
|---|---|---|
| Ser 188 | Cys 188 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 188248.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3318.1 | |
| All* | Total formula weight | 191566.2 |
