4AWJ
pVHL:EloB:EloC complex, in complex with capped Hydroxyproline
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, D, G, J) | TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2 | polymer | 104 | 11956.4 | 4 | UniProt (Q15370) Pfam (PF00240) | HOMO SAPIENS (HUMAN) | ELONGIN 18 KDA SUBUNIT, ELONGIN-B, ELOB, RNA POLYMERASE II TRANSCRIPTION FACTOR SIII SUBUNIT B, SIII P18 |
| 2 | B, E, H, K (B, E, H, K) | TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1 | polymer | 97 | 10974.6 | 4 | UniProt (Q15369) Pfam (PF03931) | HOMO SAPIENS (HUMAN) | ELONGIN 15 KDA SUBUNIT, ELONGIN-C, ELOC, RNA POLYMERASE II TRANSCRIPTION FACTOR SIII SUBUNIT C, SIII P15 |
| 3 | C, F, I, L (C, F, I, L) | VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR | polymer | 163 | 18944.4 | 4 | UniProt (P40337) Pfam (PF01847) Pfam (PF17211) | HOMO SAPIENS (HUMAN) | PROTEIN G7, PVHL |
| 4 | M, N, P, S, U... (A, B, C, F, I...) | ACETATE ION | non-polymer | 59.0 | 6 | Chemie (ACT) | |||
| 5 | O, Q, T, W (C, F, I, L) | (4R)-1-acetyl-4-hydroxy-N-methyl-L-prolinamide | non-polymer | 186.2 | 4 | Chemie (V6F) | |||
| 6 | R (F) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 7 | V (J) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence modifications
B, E, H, K: 17 - 112 (UniProt: Q15369)
C, F, I, L: 54 - 213 (UniProt: P40337)
| PDB | External Database | Details |
|---|---|---|
| Met 16 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 51 | - | expression tag |
| Ser 52 | - | expression tag |
| His 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 167501.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1251.2 | |
| All* | Total formula weight | 168752.9 |
