4AUQ

Structure of BIRC7-UbcH5b-Ub complex.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	UBIQUITIN-CONJUGATING ENZYME E2 D2	polymer	147	16766.3	2	UniProt (P62837) Pfam (PF00179)	HOMO SAPIENS (HUMAN)	UBIQUITIN CARRIER PROTEIN D2, UBIQUITIN-CONJUGATING ENZYME E2(17)KB 2, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA 2, UBIQUITIN-PROTEIN LIGASE D2
2	B, E (B, E)	BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 7	polymer	62	6852.2	2	UniProt (Q96CA5) Pfam (PF13920)	HOMO SAPIENS (HUMAN)	KIDNEY INHIBITOR OF APOPTOSIS PROTEIN, KIAP, LIVIN, MELANOMA INHIBITOR OF APOPTOSIS PROTEIN, ML-IAP, RING FINGER PROTEIN 50, BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 7 30KDA SUBUNIT, TRUNCATED LIVIN, P30-LIVIN, TLIVIN
3	C, F (C, F)	POLYUBIQUITIN-C	polymer	81	8922.1	2	UniProt (P0CG48) Pfam (PF00240)	HOMO SAPIENS (HUMAN)	UBIQUITIN
4	G, H, I, J (B, E)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
5	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	153	Chemie (HOH)

Sequence modifications

A, D: 1 - 147 (UniProt: P62837)

PDB	External Database	Details
Arg 22	Ser 22	engineered mutation
Ala 77	Asn 77	engineered mutation
Ser 85	Cys 85	engineered mutation

B, E: 239 - 298 (UniProt: Q96CA5)

PDB	External Database	Details
Gly 237	-	expression tag
Ser 238	-	expression tag

C, F: 1 - 76 (UniProt: P0CG48)

PDB	External Database	Details
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	65081.1
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	65342.7

*Water molecules are not included.