4ASK
CRYSTAL STRUCTURE OF JMJD3 WITH GSK-J1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | LYSINE-SPECIFIC DEMETHYLASE 6B | polymer | 510 | 58050.3 | 2 | UniProt (O15054) Pfam (PF02373) Pfam (PF21322) Pfam (PF21326) | HOMO SAPIENS | JMJC DOMAIN-CONTAINING PROTEIN 3, JUMONJI DOMAIN-CONTAINING PROTEIN 3, LYSINE DEMETHYLASE 6B JMJD3 |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid | non-polymer | 389.4 | 2 | Chemie (K0I) | |||
| 4 | E, H (A, B) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 1239 | Chemie (HOH) |
Sequence modifications
A, B: 1141 - 1643 (UniProt: O15054)
| PDB | External Database | Details |
|---|---|---|
| Met 1140 | - | expression tag |
| His 1644 | - | expression tag |
| His 1645 | - | expression tag |
| His 1646 | - | expression tag |
| His 1647 | - | expression tag |
| His 1648 | - | expression tag |
| His 1649 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116100.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1027.6 | |
| All* | Total formula weight | 117128.2 |
