4APF
Crystal structure of the human KLHL11-Cul3 complex at 3.1A resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | KELCH-LIKE PROTEIN 11 | polymer | 297 | 34526.2 | 1 | UniProt (Q9NVR0) Pfam (PF00651) Pfam (PF07707) In PDB | HOMO SAPIENS (HUMAN) | |
2 | B | CULLIN 3 | polymer | 388 | 45724.0 | 1 | UniProt (Q13618) Pfam (PF00888) In PDB | HOMO SAPIENS (HUMAN) | CUL-3 |
3 | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A: 67 - 340 (UniProt: Q9NVR0)
B: 23 - 388 (UniProt: Q13618)
PDB | External Database | Details |
---|---|---|
Met 44 | - | expression tag |
His 45 | - | expression tag |
His 46 | - | expression tag |
His 47 | - | expression tag |
His 48 | - | expression tag |
His 49 | - | expression tag |
His 50 | - | expression tag |
Ser 51 | - | expression tag |
Ser 52 | - | expression tag |
Gly 53 | - | expression tag |
Val 54 | - | expression tag |
Asp 55 | - | expression tag |
Leu 56 | - | expression tag |
Gly 57 | - | expression tag |
Thr 58 | - | expression tag |
Glu 59 | - | expression tag |
Asn 60 | - | expression tag |
Leu 61 | - | expression tag |
Tyr 62 | - | expression tag |
Phe 63 | - | expression tag |
Gln 64 | - | expression tag |
Ser 65 | - | expression tag |
Met 66 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 389 | - | expression tag |
Glu 390 | - | expression tag |
Asn 391 | - | expression tag |
Leu 392 | - | expression tag |
Tyr 393 | - | expression tag |
Phe 394 | - | expression tag |
Gln 395 | - | expression tag |
Ser 396 | - | expression tag |
His 397 | - | expression tag |
His 398 | - | expression tag |
His 399 | - | expression tag |
His 400 | - | expression tag |
His 401 | - | expression tag |
His 402 | - | expression tag |
Asp 403 | - | expression tag |
Tyr 404 | - | expression tag |
Lys 405 | - | expression tag |
Asp 406 | - | expression tag |
Asp 407 | - | expression tag |
Asp 408 | - | expression tag |
Asp 409 | - | expression tag |
Lys 410 | - | expression tag |
Arg 342 | Ile 342 | engineered mutation |
Asp 346 | Leu 346 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 80250.2 | |
All* | Total formula weight | 80250.2 |