4AOU
CtIDH bound to NADP. The complex structures of Isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila, support a new active site locking mechanism
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ISOCITRATE DEHYDROGENASE [NADP] | polymer | 402 | 45842.2 | 1 | UniProt (A3DC45) Pfam (PF00180) | CLOSTRIDIUM THERMOCELLUM | |
| 2 | B (A) | ISOCITRIC ACID | non-polymer | 192.1 | 1 | Chemie (ICT) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (71717786) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (165382010) | |||
| 5 | E (A) | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45842.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 959.8 | |
| All* | Total formula weight | 46802.0 |
