4AOT
Crystal Structure of Human Serine Threonine Kinase-10 (LOK) Bound to GW830263A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase 10 | polymer | 302 | 34298.6 | 2 | UniProt (O94804) Pfam (PF00069) | Homo sapiens (Human) | Lymphocyte-oriented kinase |
| 2 | C, D, E, F, H... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 3 | G, J (A, B) | 1-(4-{methyl[2-({4-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]amino}phenyl)-3-{3-[(4-methylpiperazin-1-yl)carbonyl]phenyl}urea | non-polymer | 628.7 | 2 | Chemie (GW8) | |||
| 4 | K, L (A, B) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A, B: 18 - 317 (UniProt: O94804)
| PDB | External Database | Details |
|---|---|---|
| Ser 16 | - | expression tag |
| Met 17 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68597.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1470.2 | |
| All* | Total formula weight | 70067.4 |
