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4ANP

Crystal structure of human phenylalanine hydroxylase in complex with a pharmacological chaperone

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
PHENYLALANINE-4-HYDROXYLASEpolymer32437544.51UniProt (P00439)
Pfam (PF00351)
HOMO SAPIENS (HUMAN)PHENYLALANINE HYDROXYLASE, PAH, PHE-4-MONOOXYGENASE
2B
(A)
FE (III) IONnon-polymer55.81Chemie (FE)
3C
(A)
5,6-DIMETHYL-3-(4-METHYL-2-PYRIDINYL)-2-THIOXO-2,3-DIHYDROTHIENO[2,3- D]PYRIMIDIN-4(1H)-ONEnon-polymer303.41Chemie (3QI)
4D
(A)
waterwater18.0208Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37544.5
Non-Polymers*Number of molecules2
Total formula weight359.2
All*Total formula weight37903.8
*Water molecules are not included.

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PDB entries from 2026-02-11

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