4AMA

Crystal Structure of N-acetylneuraminic acid lyase from Staphylococcus aureus with the chemical modification thia-lysine at position 165 in complex with pyruvate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	N-ACETYLNEURAMINATE LYASE	polymer	298	33861.2	4	UniProt (Q2G160) Pfam (PF00701)	STAPHYLOCOCCUS AUREUS SUBSP. AUREUS NCTC 8325	N-ACETYLNEURAMINIC ACID LYASE, N-ACETYLNEURAMINATE PYRUVATE-LYASE, N-ACETYLNEURAMINIC ACID ALDOLASE, SIALATE LYASE, SIALIC ACID ALDOLASE, SIALIC ACID LYASE
2	E, F, G, H (A, B, C, D)	water	water		18.0	356	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 293 (UniProt: Q2G160)

PDB	External Database	Details
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	135444.9
All*	Total formula weight	135444.9

*Water molecules are not included.