4AKM

Crystal structure of the human lysosome-associated membrane protein LAMP-3 (aka DC-LAMP)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 3	polymer	166	18656.7	2	UniProt (Q9UQV4) Pfam (PF01299)	HOMO SAPIENS (HUMAN)	LAMP-3, LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 3, DC-LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN, DC LAMP, PROTEIN TSC403, CD_ANTIGEN=CD208
2	C, E, F, H (A, B)	IRIDIUM (III) ION	non-polymer		192.2	4	Chemie (IR3)
3	D, G (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	I, J (A, B)	water	water		18.0	10	Chemie (HOH)

Sequence modifications

A, B: 222 - 381 (UniProt: Q9UQV4)

PDB	External Database	Details
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag
His 385	-	expression tag
His 386	-	expression tag
His 387	-	expression tag
Val 318	Ile 318	variant

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	37313.4
Non-Polymers*	Number of molecules	6
	Total formula weight	1211.3
All*	Total formula weight	38524.7

*Water molecules are not included.