4AK8
Structure of F241L mutant of langerin carbohydrate recognition domain.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER K | polymer | 155 | 17888.1 | 4 | UniProt (Q9UJ71) Pfam (PF00059) In PDB | HOMO SAPIENS (HUMAN) | LANGERIN, CD_ANTIGEN=CD207 |
| 2 | A, B, C, D | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | D | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | water | water | 18.0 | 807 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 188 - 328 (UniProt: Q9UJ71)
| PDB | External Database | Details |
|---|---|---|
| Met 174 | - | expression tag |
| Trp 175 | - | expression tag |
| Ser 176 | - | expression tag |
| His 177 | - | expression tag |
| Pro 178 | - | expression tag |
| Gln 179 | - | expression tag |
| Phe 180 | - | expression tag |
| Glu 181 | - | expression tag |
| Lys 182 | - | expression tag |
| Ile 183 | - | expression tag |
| Glu 184 | - | expression tag |
| Gly 185 | - | expression tag |
| Arg 186 | - | expression tag |
| Met 187 | - | expression tag |
| Leu 241 | Phe 241 | engineered mutation |
| Ala 278 | Val 278 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 71552.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 293.0 | |
| All* | Total formula weight | 71845.2 |
