4AJB
3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with Isocitrate, magnesium(II) and thioNADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | NADP ISOCITRATE DEHYDROGENASE | polymer | 416 | 45811.6 | 1 | UniProt (P08200) Pfam (PF00180) In PDB | ESCHERICHIA COLI | |
| 2 | A | 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 759.5 | 1 | Chemie (TAP) | |||
| 3 | A | ISOCITRIC ACID | non-polymer | 192.1 | 1 | Chemie (ICT) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | water | water | 18.0 | 490 | Chemie (HOH) |
Sequence modifications
A: 1 - 416 (UniProt: P08200)
| PDB | External Database | Details |
|---|---|---|
| Met 100 | Lys 100 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45811.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1072.0 | |
| All* | Total formula weight | 46883.5 |
