4AG3

Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with NADPH at 1.8A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG	polymer	269	28168.0	4	UniProt (O54438) Pfam (PF13561)	PSEUDOMONAS AERUGINOSA	3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE, BETA-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE, BETA-KETOACYL-ACP REDUCTASE
2	E, I, L (A, B, C)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	3	Chemie (NDP)
3	F, G, H, J, K... (A, B, C, D)	PENTAETHYLENE GLYCOL	non-polymer		238.3	8	Chemie (1PE)
4	P, Q, R, S (A, B, C, D)	water	water		18.0	477	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 247 (UniProt: O54438)

PDB	External Database	Details
Met -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Leu -9	-	expression tag
Gly -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	112671.8
Non-Polymers*	Number of molecules	11
	Total formula weight	4142.5
All*	Total formula weight	116814.3

*Water molecules are not included.