4AF0
Crystal structure of cryptococcal inosine monophosphate dehydrogenase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE | polymer | 556 | 59377.4 | 1 | UniProt (E3P6S0) | CRYPTOCOCCUS NEOFORMANS | |
| 2 | B (B) | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE | polymer | 556 | 59363.3 | 1 | UniProt (E3P6S0) | CRYPTOCOCCUS NEOFORMANS | |
| 3 | C, E (A, B) | MYCOPHENOLIC ACID | non-polymer | 320.3 | 2 | Chemie (MOA) PubChem (4272) PubChem (446541) PubChem (671222) | |||
| 4 | D, F (A, B) | INOSINIC ACID | non-polymer | 348.2 | 2 | Chemie (IMP) PubChem (177678963) PubChem (135464200) PubChem (135533971) PubChem (138454308) PubChem (135398640) PubChem (135402036) PubChem (135449337) PubChem (135486133) PubChem (135530792) PubChem (135567013) PubChem (135705234) PubChem (135854804) PubChem (135889742) PubChem (136026456) PubChem (136073920) PubChem (136217866) PubChem (136259539) PubChem (136716177) PubChem (136766861) PubChem (136811071) PubChem (137162990) PubChem (137168789) PubChem (137257909) PubChem (162510533) PubChem (174152734) | |||
| 5 | G, H (B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | I, J (A, B) | water | water | 18.0 | 515 | Chemie (HOH) |
Sequence modifications
A: 1 - 544 (UniProt: E3P6S0)
B: 1 - 544 (UniProt: E3P6S0)
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | expression tag |
| Arg -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 501 | Gly 501 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | expression tag |
| Arg -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 118740.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1529.2 | |
| All* | Total formula weight | 120269.9 |
