Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003938 | molecular_function | IMP dehydrogenase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006177 | biological_process | GMP biosynthetic process |
| A | 0006183 | biological_process | GTP biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003938 | molecular_function | IMP dehydrogenase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0006177 | biological_process | GMP biosynthetic process |
| B | 0006183 | biological_process | GTP biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MOA A 1526 |
| Chain | Residue |
| A | ASP288 |
| A | GLN470 |
| A | IMP1527 |
| A | SER289 |
| A | SER290 |
| A | ASN317 |
| A | GLY338 |
| A | MET339 |
| A | GLY340 |
| A | MET428 |
| A | GLY429 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE IMP A 1527 |
| Chain | Residue |
| A | SER86 |
| A | MET88 |
| A | ASN317 |
| A | ARG336 |
| A | GLY342 |
| A | SER343 |
| A | ILE344 |
| A | CYS345 |
| A | ASP378 |
| A | GLY379 |
| A | GLY380 |
| A | GLY401 |
| A | GLY402 |
| A | TYR425 |
| A | GLY427 |
| A | MET428 |
| A | GLY429 |
| A | GLN470 |
| A | GLY471 |
| A | MOA1526 |
| A | HOH2181 |
| A | HOH2195 |
| A | HOH2206 |
| A | HOH2208 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MOA B 1526 |
| Chain | Residue |
| B | ASP288 |
| B | SER289 |
| B | SER290 |
| B | ASN317 |
| B | GLY338 |
| B | MET339 |
| B | GLY340 |
| B | MET428 |
| B | GLY429 |
| B | GLN470 |
| B | IMP1527 |
| B | HOH2163 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE IMP B 1527 |
| Chain | Residue |
| B | SER86 |
| B | MET88 |
| B | ASN317 |
| B | ARG336 |
| B | GLY342 |
| B | SER343 |
| B | ILE344 |
| B | CYS345 |
| B | ASP378 |
| B | GLY379 |
| B | GLY380 |
| B | GLY401 |
| B | GLY402 |
| B | TYR425 |
| B | GLY427 |
| B | MET428 |
| B | GLY429 |
| B | GLN470 |
| B | GLY471 |
| B | MOA1526 |
| B | HOH2177 |
| B | HOH2199 |
| B | HOH2201 |
| B | HOH2202 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1528 |
| Chain | Residue |
| B | THR4 |
| B | ASN5 |
| B | PRO9 |
| B | PRO10 |
| B | HOH2003 |
| B | HOH2004 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1529 |
| Chain | Residue |
| B | LEU25 |
| B | GLU26 |
| B | TYR28 |
| B | ARG30 |
| B | GLY31 |
| B | HOH2178 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. LRIGMGsGSICiT |
| Chain | Residue | Details |
| B | LEU335-THR347 | |
| A | LEU335-THR347 | |
