4AEZ
Crystal Structure of Mitotic Checkpoint Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, D, G) | WD REPEAT-CONTAINING PROTEIN SLP1 | polymer | 401 | 43980.9 | 3 | UniProt (P78972) Pfam (PF00400) | SCHIZOSACCHAROMYCES POMBE (FISSION YEAST) | CDC20 |
| 2 | B, E, H (B, E, H) | MITOTIC SPINDLE CHECKPOINT COMPONENT MAD2 | polymer | 203 | 23482.9 | 3 | UniProt (O14417) Pfam (PF02301) | SCHIZOSACCHAROMYCES POMBE (FISSION YEAST) | MAD2 |
| 3 | C, F, I (C, F, I) | MITOTIC SPINDLE CHECKPOINT COMPONENT MAD3 | polymer | 223 | 26377.5 | 3 | UniProt (O59767) Pfam (PF08311) | SCHIZOSACCHAROMYCES POMBE (FISSION YEAST) | MAD3 |
| 4 | J, K, L, M, N... (A, B, C, D, E...) | water | water | 18.0 | 318 | Chemie (HOH) |
Sequence modifications
B, E, H: 1 - 203 (UniProt: O14417)
| PDB | External Database | Details |
|---|---|---|
| Ala 12 | Leu 12 | engineered mutation |
| Ala 133 | Arg 133 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 281523.9 | |
| All* | Total formula weight | 281523.9 |






