4AEL
PDE10A in complex with the inhibitor AZ5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE 10A | polymer | 344 | 39465.2 | 2 | UniProt (Q9Y233) In PDB | HOMO SAPIENS (HUMAN) | |
2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | A, B | 2-(2'-ETHOXYBIPHENYL-4-YL)-4-HYDROXY-1,6-NAPHTHYRIDINE-3-CARBONITRILE | non-polymer | 367.4 | 2 | Chemie (4HN) | |||
5 | water | water | 18.0 | 313 | Chemie (HOH) |
Sequence modifications
A, B: 448 - 789 (UniProt: Q9Y233)
PDB | External Database | Details |
---|---|---|
Ser 446 | - | expression tag |
Asn 447 | - | expression tag |
Ala 448 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 78930.4 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 914.2 | |
All* | Total formula weight | 79844.7 |