4AE1
Crystal structure of diphtheria toxin mutant CRM197 in complex with nicotinamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DIPHTHERIA TOXIN | polymer | 535 | 58483.4 | 2 | UniProt (P00588) Pfam (PF02763) Pfam (PF02764) Pfam (PF01324) | CORYNEBACTERIUM DIPHTHERIAE | DT, NAD(+)--DIPHTHAMIDE ADP-RIBOSYLTRANSFERASE, DIPHTHERIA TOXIN FRAGMENT A, DIPHTHERIA TOXIN FRAGMENT B, CRM197 |
| 2 | C, D (A, B) | NICOTINAMIDE | non-polymer | 122.1 | 2 | Chemie (NCA) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 252 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 535 (UniProt: P00588)
| PDB | External Database | Details |
|---|---|---|
| Glu 52 | Gly 53 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116966.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 244.3 | |
| All* | Total formula weight | 117211.1 |
