4ABJ
Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amide bond
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CATIONIC TRYPSIN | polymer | 223 | 23324.3 | 1 | UniProt (P00760) Pfam (PF00089) | BOS TAURUS (CATTLE) | BETA-TRYPSIN, ALPHA-TRYPSIN CHAIN 1, ALPHA-TRYPSIN CHAIN 2 |
| 2 | B (B) | TRYPSIN INHIBITOR 1 | polymer | 13 | 1533.8 | 1 | UniProt (Q4GWU5) BIRD (PRD_000846) | HELIANTHUS ANNUUS | ICA-SFTI INHIBITOR, SFTI-1 |
| 3 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D (A) | DIMETHYLFORMAMIDE | non-polymer | 73.1 | 1 | Chemie (DMF) | |||
| 5 | E, F, G, H (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | I (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | J (A) | water | water | 18.0 | 282 | Chemie (HOH) |
Sequence modifications
B: 1 - 13 (UniProt: Q4GWU5)
| PDB | External Database | Details |
|---|---|---|
| Plw 7 | Ile 46 | SEE REMARK 999 |
| Plw 7 | Pro 47 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 24858.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 577.6 | |
| All* | Total formula weight | 25435.7 |
