Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1247 |
| Chain | Residue |
| A | GLU75 |
| A | ASN77 |
| A | VAL80 |
| A | GLU85 |
| A | HOH2113 |
| A | HOH2114 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMF A 1248 |
| Chain | Residue |
| A | HOH2146 |
| A | HOH2159 |
| A | ASN100 |
| A | THR103 |
| A | ASN105 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1249 |
| Chain | Residue |
| A | GLN138 |
| A | CYS139 |
| A | LYS162 |
| A | VAL205 |
| A | CYS206 |
| A | SER207 |
| A | GLY208 |
| A | HOH2198 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 1250 |
| Chain | Residue |
| A | HIS46 |
| A | ILE78 |
| A | ALA135 |
| A | TYR154 |
| A | HOH2049 |
| A | HOH2122 |
| A | HOH2199 |
| A | HOH2200 |
| A | HOH2281 |
| B | PLW7 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1251 |
| Chain | Residue |
| A | ALA133 |
| A | ILE165 |
| A | ASP168 |
| A | PHE184 |
| A | LYS231 |
| A | HOH2192 |
| A | HOH2215 |
| A | HOH2222 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1252 |
| Chain | Residue |
| A | PRO155 |
| A | ASP156 |
| A | VAL157 |
| A | LYS159 |
| A | HOH2202 |
| A | HOH2283 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1253 |
| Chain | Residue |
| A | LYS172 |
| A | PRO176 |
| A | GLY177 |
| A | GLN241 |
| A | HOH2231 |
| A | HOH2232 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL59-CYS64 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP194-VAL205 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 220 |
| Details | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Reactive bond","evidences":[{"source":"UniProtKB","id":"P81705","evidenceCode":"ECO:0000250"}]} |
