4A9I

N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 3-methyl-1,2,3,4- tetrahydroquinazolin-2-one

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	BROMODOMAIN CONTAINING 2	polymer	154	17908.7	3	UniProt (P25440) Pfam (PF00439) In PDB	HOMO SAPIENS (HUMAN)	HUMAN BRD2
2	A, B, C	1-[1-(PYRIDIN-2-YL)INDOLIZIN-3-YL]ETHAN-1-ONE	non-polymer		237.3	3	Chemie (P9I)
3	A, C	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	B	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5		water	water		18.0	233	Chemie (HOH)

Sequence modifications

A, B, C: 67 - 200 (UniProt: P25440)

PDB	External Database	Details
Gly 47	-	expression tag
Ser 48	-	expression tag
Ser 49	-	expression tag
His 50	-	expression tag
His 51	-	expression tag
His 52	-	expression tag
His 53	-	expression tag
His 54	-	expression tag
His 55	-	expression tag
Ser 56	-	expression tag
Ser 57	-	expression tag
Gly 58	-	expression tag
Leu 59	-	expression tag
Val 60	-	expression tag
Pro 61	-	expression tag
Arg 62	-	expression tag
Gly 63	-	expression tag
Ser 64	-	expression tag
His 65	-	expression tag
Met 66	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	53726.2
Non-Polymers*	Number of molecules	7
	Total formula weight	1062.1
All*	Total formula weight	54788.3

*Water molecules are not included.