4A6L
beta-tryptase inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | TRYPTASE ALPHA/BETA-1 | polymer | 245 | 27491.4 | 4 | UniProt (Q15661) Pfam (PF00089) UniProt (by SIFTS) (P20231) In PDB | HOMO SAPIENS (HUMAN) | TRYPTASE-1, TRYPTASE I, TRYPTASE ALPHA-1, BETA-TRYPTASE |
| 2 | A, B, C, D | 1-{3-[1-({5-[(2-fluorophenyl)ethynyl]furan-2-yl}carbonyl)piperidin-4-yl]phenyl}methanamine | non-polymer | 402.5 | 4 | Chemie (P43) | |||
| 3 | water | water | 18.0 | 366 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 16 - 265 (UniProt: Q15661)
| PDB | External Database | Details |
|---|---|---|
| Lys 120 | Asn 132 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 109965.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1609.8 | |
| All* | Total formula weight | 111575.5 |
