Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0031012 | cellular_component | extracellular matrix |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0031012 | cellular_component | extracellular matrix |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005615 | cellular_component | extracellular space |
| C | 0006508 | biological_process | proteolysis |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0008236 | molecular_function | serine-type peptidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0031012 | cellular_component | extracellular matrix |
| D | 0004252 | molecular_function | serine-type endopeptidase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005615 | cellular_component | extracellular space |
| D | 0006508 | biological_process | proteolysis |
| D | 0008233 | molecular_function | peptidase activity |
| D | 0008236 | molecular_function | serine-type peptidase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE P43 A 1263 |
| Chain | Residue |
| A | GLN105 |
| A | TRP233 |
| A | GLY234 |
| A | GLU235 |
| A | GLY237 |
| A | HOH2053 |
| C | ASP64 |
| C | TYR102 |
| A | TYR181 |
| A | ILE193 |
| A | ASP207 |
| A | SER208 |
| A | CYS209 |
| A | GLN210 |
| A | SER213 |
| A | VAL231 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE P43 B 1263 |
| Chain | Residue |
| B | GLN105 |
| B | TYR181 |
| B | ILE193 |
| B | ASP207 |
| B | SER208 |
| B | CYS209 |
| B | SER213 |
| B | VAL231 |
| B | TRP233 |
| B | GLY234 |
| B | GLU235 |
| B | GLY237 |
| B | HOH2086 |
| D | ASP64 |
| D | TYR102 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE P43 C 1263 |
| Chain | Residue |
| A | ASP64 |
| A | TYR102 |
| C | GLN105 |
| C | TYR181 |
| C | ILE193 |
| C | ASP207 |
| C | SER208 |
| C | CYS209 |
| C | GLN210 |
| C | SER213 |
| C | VAL231 |
| C | TRP233 |
| C | GLY234 |
| C | GLU235 |
| C | GLY237 |
| C | ARG243 |
| C | GLY245 |
| C | HOH2080 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE P43 D 1263 |
| Chain | Residue |
| B | ASP64 |
| B | TYR102 |
| D | GLN105 |
| D | TYR181 |
| D | ILE193 |
| D | ASP207 |
| D | SER208 |
| D | SER213 |
| D | VAL231 |
| D | TRP233 |
| D | GLY234 |
| D | GLU235 |
| D | GLY237 |
| D | GLY245 |
| D | HOH2077 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU55-CYS60 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| A | ASP207-VAL218 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 964 |
| Details | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P21845","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
4A6L
