4A6D
Crystal structure of human N-acetylserotonin methyltransferase (ASMT) in complex with SAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HYDROXYINDOLE O-METHYLTRANSFERASE | polymer | 353 | 39478.8 | 1 | UniProt (P46597) Pfam (PF16864) Pfam (PF00891) In PDB | HOMO SAPIENS (HUMAN) | N-ACETYL SEROTONIN METHYLTRANSFERASE, HIOMT, ACETYLSEROTONIN O-METHYLTRANSFERASE, ASMT |
| 2 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 67 | Chemie (HOH) |
Sequence modifications
A: 1 - 345 (UniProt: P46597)
| PDB | External Database | Details |
|---|---|---|
| Gly 346 | - | expression tag |
| Thr 347 | - | expression tag |
| His 348 | - | expression tag |
| His 349 | - | expression tag |
| His 350 | - | expression tag |
| His 351 | - | expression tag |
| His 352 | - | expression tag |
| His 353 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39478.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1005.6 | |
| All* | Total formula weight | 40484.4 |
