4A6A
A115V variant of dCTP deaminase-dUTPase from Mycobacterium tuberculosis in complex with dTTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE | polymer | 190 | 20919.7 | 12 | UniProt (O07247) Pfam (PF22769) UniProt (by SIFTS) (P9WP17) | MYCOBACTERIUM TUBERCULOSIS | DCTP DEAMINASE, DCTP DEAMNIASE-DUTPASE |
| 2 | BA, EA, GA, IA, KA... (H, I, J, K, L...) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 12 | Chemie (TTP) | |||
| 3 | AA, CA, DA, FA, HA... (G, H, I, J, K...) | MAGNESIUM ION | non-polymer | 24.3 | 14 | Chemie (MG) | |||
| 4 | MA, NA, OA, PA, QA... (A, B, D, G, H...) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 190 (UniProt: O07247)
| PDB | External Database | Details |
|---|---|---|
| Val 115 | Ala 115 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 251035.9 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 6126.3 | |
| All* | Total formula weight | 257162.2 |
