4A59

Crystal structure of Toxoplasma gondii nucleoside triphosphate diphosphohydrolase 3 (NTPDase3) in complex with AMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	NUCLEOSIDE-TRIPHOSPHATASE 1	polymer	611	67657.9	4	UniProt (Q27893) Pfam (PF01150)	TOXOPLASMA GONDII	NTPDASE3, NTPASE-I, NUCLEOSIDE TRIPHOSPHATE HYDROLASE 1, NUCLEOSIDE-TRIPHOSPHATASE I
2	E, F, G, H, I (A, B, C, D)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	5	Chemie (AMP)
3	J, K, L, M (A, B, C, D)	water	water		18.0	884	Chemie (HOH)

Sequence modifications

A, B, C, D: 26 - 628 (UniProt: Q27893)

PDB	External Database	Details
Met 25	-	expression tag
Glu 629	-	expression tag
His 630	-	expression tag
His 631	-	expression tag
His 632	-	expression tag
His 633	-	expression tag
His 634	-	expression tag
His 635	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	270631.7
Non-Polymers*	Number of molecules	5
	Total formula weight	1736.1
All*	Total formula weight	272367.8

*Water molecules are not included.